Sulfad

মন্তব্যসমূহ

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Sulfad

ছবি
  The structure of 2,4-(4′-aminobenzenamine)pyrimidine (1), a pyrimidine alkaloid previously isolated from the bulbs of Scilla madeirensis (Asparagaceae, synonym Autonoë madeirensis), has been revised. These conclusions were met via comparison of reported NMR and EIMS data with those obtained from synthetic standards. The Sulfad structure is the antibiotic sulfadiazine (2), which has likely been isolated as a contaminant from the site of collection. The reported bioactivity of 1 as an α1-adrenoceptor antagonist should instead be ascribed to sulfadiazine. Our findings appear to show another example of an anthropogenic contaminant being identified as a natural product and emphasize the importance of considering the biosynthetic origins of isolated compounds within a phylogenetic context. The reported isolation of the analgesic tramadol from the roots of the African medicinal plant Nauclea latifolia Sm. (Rubiaceae) in 2013 (1) garnered substantial attention from the scientific communi...
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Sulfad

ছবি
  Sulfadiazine is a short-acting sulfonamide. It is readily absorbed from the gastrointestinal tract and rapidly excreted by the kidney. As with other sulfonamides, there are few specific indications because of the wide range of safer and more effective alternative antibiotics. In addition, the emergence of resistance to the sulfonamides has rendered this drug class unsuitable for the treatment of many infections that responded to them in the past. Sulfadiazine is used Sulfad to treat urinary tract infections and as an adjunct for the treatment of a few parasitic diseases. Although sulfadiazine, like other sulfonamides, is fairly well tolerated, its use is associated with adverse effects. Hypersensitivity reactions and gastrointestinal upset are among the common side effects associated with sulfadiazine. Fundamentals: Ligands, Complexes, Synthesis, Purification, and Structure Z. Xu, L.K. Thompson, in Comprehensive Coordination Chemistry II, 2003 1.5.2.1 Overview Diazine (N–N) brid...
আরও পড়ুন

Sulfad

ছবি
  Sulfadiazine is a short-acting sulfonamide. It is readily absorbed from the gastrointestinal tract and rapidly excreted by the kidney. As with other sulfonamides, there are few specific indications because of the wide range of safer and more effective alternative antibiotics. In addition, the emergence of resistance to the sulfonamides has rendered this drug class unsuitable for the treatment of many infections that responded to them in the past. Sulfadiazine is used Sulfad to treat urinary tract infections and as an adjunct for the treatment of a few parasitic diseases. Although sulfadiazine, like other sulfonamides, is fairly well tolerated, its use is associated with adverse effects. Hypersensitivity reactions and gastrointestinal upset are among the common side effects associated with sulfadiazine. Fundamentals: Ligands, Complexes, Synthesis, Purification, and Structure Z. Xu, L.K. Thompson, in Comprehensive Coordination Chemistry II, 2003 1.5.2.1 Overview Diazine (N–N) brid...
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